Health
Minor cannabinoids: a new hope for dermatological diseases
A groundbreaking review of studies is shedding light on the therapeutic potential of lesser-known hemp- and cannabis-derived cannabinoids such as THCV, CBDV, CBC, CBM and CBN. According to a literature review published in the journal “Molecules”, minor cannabinoids offer interesting perspectives for the treatment of dermatological diseases. These compounds could be the key to alleviating the symptoms of pathologies such as psoriasis, dermatitis, eczema or acne, which can have a huge impact on the quality of life of patients who suffer from them.
The review, conducted by Polish researchers Emilia Kwiecień and Dorota Kowalczuk, from the Faculty of Pharmacy at the University of Lublin, Poland, highlights the potential of these lesser-known cannabinoids to revolutionize dermatological therapies.
Researchers have identified a myriad of minor cannabinoids, including CBDV (Cannabidivarin), CBDP (Cannabidiphorol), CBC (Cannabicromene), THCV (Tetrahydrocannabivarin), CBGA (Cannabigerolic Acid), CBG (Cannabigerol) and CBN (Cannabinol). Recent additions to this list include CBM (Cannabimovone) and CBE (Cannabielsoíne).
Through a meticulous examination of the existing scientific literature, Kwiecień and Kowalczuk unearthed a treasure trove of evidence. These minor cannabinoids exhibit a wide range of pharmacological activities, including anti-inflammatory, analgesic, antimicrobial and anti-itching properties. Numerous studies have highlighted its effectiveness in relieving symptoms associated with skin conditions such as psoriasis, eczema, acne and itching.
Customized treatments with minor cannabinoids
Certain minor cannabinoids have shown a notable affinity with specific dermatological diseases. For example, CBDV (Cannabidivarin), known for its anti-inflammatory properties, is emerging as a potential solution to treat itching and swelling in atopic dermatitis (AD). In addition, the anti-inflammatory and anti-oxidant properties of this cannabinoid suggest a healing effect on acne lesions.
Recently discovered CBM (Cannabimovone) and CBE (Cannabielsoin, a CBD metabolite) have anti-inflammatory potential. These compounds promise to open new horizons in scientific research for various diseases, which are often disabling for those who suffer from them. Likewise, CBC (Cannabichromene), with its anti-inflammatory and antioxidant effects, could prove invaluable in the treatment of acne, psoriasis and even Alzheimer's disease.
THCV: the trump card for acne
The minor cannabinoid THCV (Δ9-Tetrahydrocannabivarin) emerges as a beacon of hope in the battle against acne. Its potential to regulate sebum production, combined with its anti-inflammatory and antibacterial properties, positions it as a formidable competitor in the fight against the development of acne breakouts.
The beneficial effects of minor cannabinoids on the skin are believed to result from interaction with the body's endocannabinoid system. This central regulatory system plays a key role in maintaining the health and functionality of organisms. It exerts influence on various skin functions, including immune response, cell proliferation, differentiation and survival. Perhaps most notably, it has a robust ability to suppress skin inflammation. Interestingly, topical applications of minor cannabinoids may extend their benefits to mitigating the effects of aging, but this possibility requires further investigation.
the way forward
While the discovery of the benefits of minor cannabinoids in dermatological care is promising, caution is essential. More research is needed to fully validate its effectiveness and safety. It also has to address numerous challenges, including its impact on the nervous system, product quality and regulation, as well as complex ethical and legal considerations. Thus, it becomes imperative to adopt a balanced approach that maximizes benefits and minimizes potential risks to health and society.
In conclusion, the study's revealing data open up interesting avenues for the integration of minor cannabinoids in dermatological treatments. With rigorous research and a cautious approach, then you can unlock its full potential, offering hope and relief to countless people who struggle with skin problems on a daily basis.
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[Disclaimer: Please note that this text was originally written in Portuguese and is translated into English and other languages using an automatic translator. Some words may differ from the original and typos or errors may occur in other languages.]____________________________________________________________________________________________________
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With a professional background in CAD technical drawing (2D and 3D), João Xabregas is an activist and advocate for all uses and applications of cannabis. He discovered and entered the world of cannabis during his youth, where he developed a special interest in the cultivation of the plant, which led him on a journey of self-learning through the world of cannabis that continues to this day. His adventures linked to cannabis cultivation began with the same goal as many others: to be able to guarantee the quality and eliminate any possible risks to his health of what he consumed, as well as to avoid any type of dependence on the illicit market. However, he quickly began to view the world of cannabis and everything related to it with a very different perspective. He admits the enormous passion he has for the most persecuted plant in the world and about which he is always willing to write and have a good conversation.
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