Connect with us

Health

CBD and CBC show promising results in head and neck squamous cell carcinoma

Published

em

Listen to this article

study published in the journal Cancers discovered that cannabis extracts rich in CBD (cannabidiol) can kill head and neck cancer cells. Research examined the anti-tumor effects of 24 different cannabis extracts on head and neck squamous cell carcinoma and found that CBD-dominant extracts can induce apoptosis and kill cancer cells. The combination of CBD with cannabichromene (CBC), in a 2:1 ratio, made the effect even stronger.

Head and neck squamous cell carcinoma (abbreviated to HNSCC) is the sixth most common cancer worldwide and accounts for more than 90% of head and neck cancers. Despite significant advances in cancer screening and prevention, HNSCC is still responsible for approximately 450.000 deaths per year worldwide.

The researchers believe that the results of the pre-clinical study suggest that cannabis extracts already used in palliative care to manage symptoms may have an additional, previously unknown, anti-cancer effect.

Israel: one of the main countries leading cannabis research

The study was carried out and completed in 2023 by researchers from various departments at two Israeli Universities, the Hebrew University of Jerusalem and the Technion-Israel Institute of Technology, with extracts provided by Cannasoul Analytics. The research concluded that CBD-dominant decarboxylated extracts caused a significant increase in cell death in all HNSCC cell lines that were tested. The effect was dose-dependent, with a greater percentage of cells dying when higher concentrations of extract were applied.

The researchers confirmed that this cell death was the result of the extracts that induced apoptosis. When CBD was combined with CBC or THC, the effect on cancer cells increased to match that of the complete extract. The researchers determined that a combination of CBD-CBC or CBD-THC in a 2:1 ratio was the most potent in terms of its cytotoxicity.

The researchers point out that medical cannabis is already being used in many areas as a palliative treatment for cancer patients. “Based on this research, these chemovars (chemically and genetically distinct cannabis strains) may provide additional anticancer properties in addition to the palliative effects that cancer patients may benefit from,” they wrote. “In addition, we recommend extracts enriched with CBC to achieve a CBD/CBC ratio of (2:1) to maximize the cytotoxic effect in HNSCC.”

Although more research is needed to determine the exact mechanism of action, the results of this study suggest that CBD-rich cannabis extracts may have potential as a new therapy for HNSCC.

 

____________________________________________________________________________________________________

[Disclaimer: Please note that this text was originally written in Portuguese and is translated into English and other languages ​​using an automatic translator. Some words may differ from the original and typos or errors may occur in other languages.]

____________________________________________________________________________________________________

What do you do with €3 a month? Become one of our Patrons! If you believe that independent cannabis journalism is necessary, subscribe to one of the levels of our Patreon account and you will have access to unique gifts and exclusive content. If there are many of us, we can make a difference with little!

Click here to comment
Subscribe
Notify of

0 Comments
Inline feedback
View all comments
Advertising


Watch the Documentary "Patients"

Documentary Patients Laura Ramos help us grow

Mais recentes

International3 days ago

Paul Bergholts, alleged leader of Juicy Fields, detained in the Dominican Republic

Paul Bergholts, the alleged leader of the Juicy Fields pyramid scheme, has been detained in the Dominican Republic and will be subjected to...

Health6 days ago

Cannabinoids reveal promising results in the treatment of Borderline Personality Disorder

An investigation carried out by Khiron LifeSciences and coordinated by Guillermo Moreno Sanz suggests that medicines based on...

International6 days ago

Juicy Fields case: 9 detained by Europol and Eurojustice. Scam exceeds 645 million euros

A joint investigation conducted by several European authorities, supported by Europol and Eurojust, culminated in the arrest of nine suspects...

International1 weeks ago

Regular cannabis users may require more anesthesia during medical procedures

Regular cannabis users may require more anesthesia during medical procedures to remain sedated compared to...

International1 weeks ago

The future of CBD in Japan: How legal reforms will shape the market

Late last year, Japan took a big step towards cannabis reform after approving...

National2 weeks ago

Portugal: GreenBe Pharma obtains EuGMP certification at Elvas facilities

GreenBe Pharma, a medical cannabis company located in Elvas, Portugal, has obtained EU-GMP certification under...

National2 weeks ago

Álvaro Covões, from Everything is New, buys Clever Leaves facilities in Alentejo for 1.4 million euros

Álvaro Covões, founder and CEO of the show promotion agency 'Everything is New', which organizes one of the biggest festivals in...

Events2 weeks ago

ICBC returns to Berlin on April 16th and 17th

It is one of the largest and most recognized B2B cannabis conferences in Europe and returns to Berlin in...

International2 weeks ago

The legalization of cannabis in Germany seen through the eyes of the hacker who created an essential map

A hacker from Koblenz, a city in the state of Rhineland-Palatinate, created a map with the places where, from...

National2 weeks ago

André Ventura says he wants to “Clean up all cannabis in Portugal”

André Ventura, the well-known leader of the far-right Portuguese political party Chega, has said he wants to “cleanse all cannabis from...